Protective effect of injection of Danhong against acute myocardial ischemia in dogs / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 1463-1465, 2008.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-264854
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the protective effects of injection of Danhong against acute myocardial ischemia in dogs.</p><p><b>METHOD</b>The myocardial ischemia model were established by ligation of coronary artery in dogs. The degree of myocardial ischemia and the myocardial infarction size were observed before and after giving injection of Danhong. The serum creatine phosphokinase (CK) and lactate dehydrogenase (LDH) activities were also determined.</p><p><b>RESULT</b>Injection of Danhong (1, 2, 4 g x kg(-1)) could significantly decreased the damage degree of myocardial ischemia, redused myocardial infarction size and also reduced the serum LDH and CK activities.</p><p><b>CONCLUSION</b>Injection of Danhong had protective action on myocardial ischemia.</p>
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Pharmacology
/
Blood
/
Drugs, Chinese Herbal
/
Myocardial Ischemia
/
Creatine Kinase
/
Drug Therapy
/
Injections
/
L-Lactate Dehydrogenase
/
Myocardial Infarction
Limits:
Animals
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2008
Document type:
Article