Transurethral resection of the prostate for advanced hormone-refractory prostate cancer: a feasibility study / 中华男科学杂志
National Journal of Andrology
; (12): 55-58, 2011.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-266211
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the effect of transurethral resection of the prostate (TURP) in the treatment of advanced prostate cancer with bladder outlet obstruction (BOO).</p><p><b>METHODS</b>We included in this study 43 cases of advanced prostate cancer with BOO treated by TURP, and analyzed their IPSS, maximum urinary flow rate and relevant risk factors pre-operatively and at 3 and 12 months after TURP.</p><p><b>RESULTS</b>Compared with the baseline, IPSS and the maximum urinary flow rate of the patients showed significant differences 3 months after surgery ([19.60 +/- 0.41] score vs. [9.58 +/- 0.33] score, [4.93 +/- 0.68] ml/s vs. [8.96 +/- 0.47] ml/s, P < 0.05), but not at 12 months ([15.73 +/- 0.66] score, [5.67 +/- 0.44] ml/s). In multiple regression analysis, a good outcome was associated with pre-operative acute urinary retention, while poor prognosis with hormone-refractory prostate cancer.</p><p><b>CONCLUSION</b>In the treatment of advanced hormone-refractory prostate cancer with BOO, TURP can reduce IPSS and increase the maximum urinary flow rate in the early period after surgery, but its long-term effect is not so desirable. Meanwhile the operation itself may bring about relevant complications and reduce the patient's quality of life.</p>
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Prostatic Neoplasms
/
General Surgery
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Urinary Bladder Neck Obstruction
/
Feasibility Studies
/
Treatment Outcome
/
Transurethral Resection of Prostate
Type of study:
Prognostic study
/
Risk factors
Aspects:
Patient-preference
Limits:
Aged
/
Aged, 80 and over
/
Humans
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Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2011
Document type:
Article