Progress in researches on male immunocontraception / 中华男科学杂志
National Journal of Andrology
; (12): 1129-1132, 2013.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-267973
Responsible library:
WPRO
ABSTRACT
The ideal goal of male immunocontraception is to develop a safe, effective, convenient, acceptable and reversible contraceptive vaccine. Current studies mainly focus on screening the most suitable target antigens from reproductive hormones and sperm functional proteins for the development of immuno contraceptive vaccines. The vaccine targeting reproductive hormones has not been widely used due to its different degrees of side effects and complicated operation. Recent studies show the practicability and applicability of the immuno contraceptive vaccine targeting sperm specific antigens, but its development is confronted with many challenges, such as how to select appropriate target antigens, how to enhance the immunogenicity of the vaccine, how to choose appropriate drug-delivery ways, how to reduce its side effects, and how to decrease its cost.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Vaccines
/
Contraception, Immunologic
/
Contraceptive Agents, Male
/
Allergy and Immunology
/
Methods
/
Antigens
Limits:
Humans
/
Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2013
Document type:
Article