Therapeutic efficacy of strontium-89-chloride for bone metastatic tumors without bone pain / 南方医科大学学报
Journal of Southern Medical University
; (12): 390-391, 2007.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-268125
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the safety and efficacy of strontium-89-chloride for management of bone metastases in patients without bone pain.</p><p><b>METHODS</b>Fifty-four patients without painful bone metastases were given a single intravenous dose (1.48-2.22 MBq/kg) of strontium-89-chloride, which was repeated once or twice at the interval between 3 and 6 months.</p><p><b>RESULTS</b>The total response rate was 74.0% in these, and the response rate was significantly lower in patients with focal size>2 cm than in those with focal size<or=2 cm (33.3% vs 66.6%, chi2=14.9, P<0.01). The side effects of strontium-89-chloride included mainly thrombocytopenia and neutropenia, mostly mild and reversible without interventions.</p><p><b>CONCLUSION</b>Strontium-89-chloride is effective and safe for treatment of nonpainful bone metastases.</p>
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Pain
/
Pathology
/
Prostatic Neoplasms
/
Radiotherapy
/
Strontium Radioisotopes
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Bone Neoplasms
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Treatment Outcome
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Therapeutic Uses
/
Lung Neoplasms
Limits:
Adult
/
Aged
/
Aged, 80 and over
/
Female
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Humans
/
Male
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2007
Document type:
Article