Biology of thioredoxin and its association with Alzheimer's disease and Parkinson's disease / 药学学报
Acta Pharmaceutica Sinica
; (12): 1-8, 2008.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-268181
Responsible library:
WPRO
ABSTRACT
Thioredoxin (Trx) is a crucial protein for antioxidative defense, as well as a redox regulator of the intra- and extracellular signaling pathways and transcription factors. In this review, we focus on mammalian Trx and its association with Alzheimer's disease (AD) and Parkinson's disease (PD). Based on the evidence of neuroprotective effects of Trx, up-regulation of Trx may be a good strategy for prevention and treatment of AD and PD.
Full text:
Available
Health context:
SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases
Health problem:
Alzheimer’s Disease and other Dementias
/
Mental Health and Behavioral Disorders
/
Parkinson Disease
Database:
WPRIM (Western Pacific)
Main subject:
Oxidation-Reduction
/
Parkinson Disease
/
Physiology
/
Thioredoxins
/
Apoptosis
/
Neuroprotective Agents
/
Alzheimer Disease
/
Metabolism
/
Antioxidants
Limits:
Animals
/
Humans
Language:
Chinese
Journal:
Acta Pharmaceutica Sinica
Year:
2008
Document type:
Article
