Photodynamic Therapy for Chronic Central Serous Chorioretinopathy: Multicenter Study of 65 Cases
Journal of the Korean Ophthalmological Society
; : 390-398, 2009.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-26839
Responsible library:
WPRO
ABSTRACT
PURPOSE:
To determine the effect of photodynamic therapy (PDT) on patients with chronic central serous chorioretinopahty (CSC).METHODS:
This was a retrospective multicenter study. We collected demographic and ophthalmic data for patients with chronic CSC who were treated with PDT from 16 institutions in Korea. The best corrected visual acuity (BCVA), ophthalmoscopic finding and optical coherence tomography at baseline and follow-up visits were compared longitudinally.RESULTS:
Sixty-five eyes of 65 patients were recruited. Males (51 patients, 78.5%) outnumbered females (14 patients, 21.5%). The mean age was 46.4+/-10.0 years of age (28~69). By 1 month, mean BCVA improved from 0.47 to 0.37 (logarithm of the minimum angle of resolution) (P <0.01). This BCVA increased throughout 6 months. Subretinal fluid resolved partially or completely in 89.1% of the patients. Central macular thickness (CMT) decreased from 303.4 to 168.7 micrometer. The amount of change in CMT after PDT was correlated to the female sex and prePDT CMT. At 3 months after PDT, the amount of change in BCVA was significantly related to that of change of CMT (p <0.05). Adverse events were reported in 4 cases, however, most were mild.CONCLUSIONS:
PDT was effective and safe for treating chronic CSC.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Photochemotherapy
/
Triazenes
/
Visual Acuity
/
Retrospective Studies
/
Follow-Up Studies
/
Tomography, Optical Coherence
/
Eye
/
Subretinal Fluid
/
Korea
Type of study:
Observational study
/
Prognostic study
Limits:
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
Korean
Journal:
Journal of the Korean Ophthalmological Society
Year:
2009
Document type:
Article