Analysis of sodium benzoate biotoxicity by atomic force microscope / 生物工程学报
Chinese Journal of Biotechnology
; (12): 1428-1432, 2008.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-275367
Responsible library:
WPRO
ABSTRACT
Atomic force microscope (AFM) was used to study biotoxicity of food preservative sodium benzoate (SB) at the single cellular level. Lymphocyte morphology and membrane ultrastructure treated with SB at different concentrations and time were analyzed visually. As compared to the normal lymphocyte, the cell morphology and membrane was significantly changed and its ultrastructure was also complicated. After treated with SB, the Rp-v, Rq, Ra and Z values were changed. The statistical analysis of lymphocytes after treated with SB was studied, and discussed its mechanism.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Lymphocytes
/
Cell Membrane
/
Microscopy, Atomic Force
/
Sodium Benzoate
/
Toxicity
/
Mice, Inbred BALB C
Limits:
Animals
Language:
Chinese
Journal:
Chinese Journal of Biotechnology
Year:
2008
Document type:
Article