Experimental study of preventing postoperative stenosis by modifying artificial esophagus in dogs / 中国医学科学院学报

ABSTRACT

<p><b>OBJECTIVE</b>To observe the effect of the modified artificial esophagus on postoperative stenosis in dogs.</p><p><b>METHODS</b>The models of defected esophagus were established in dogs. The double-layered membrane tube (modifying type) was implanted in the test group (n = 10) and the esophageal stent was further inserted when the stenosis occurred. The single pattern tube (original type) was transplanted to the control group (n = 30). The dilation treatment was performed to relieve the postoperative stenosis; alternatively, the esophageal stent was implanted in the unsuccessful dogs.</p><p><b>RESULTS</b>The average artificial esophagus removal time was 19.10 days in the test group, which was significantly lower than 39.07 days in the control group (t = 15.6, P = 0.000). No obstruction after removal was observed in the experimental group. The incidence of postoperative stenosis had no significant difference between these two groups.</p><p><b>CONCLUSION</b>The double-layered membrane tube can make the tube removal safer by shortening the removal time.</p>