Polymorphism of fifteen short tandem repeat loci in Maonan minority of Guangxi / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
; (6): 97-100, 2007.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-285023
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the genetic polymorphism of 15 short tandem repeat (STR) (D2S1338ì D3S1358ì D5S818ì D7S820, D8S1179, D13S317, D16S539, D18S51, D19S433, D21S11, CSF1PO, TPOX, TH01, vWA, FGA) in Maonan minority of Guangxi province.</p><p><b>METHODS</b>The allele frequencies and the genotype of 15 STR loci were analyzed in 143 unrelated individuals in Maonan minority of Guangxi by PCR-STR and genescan.</p><p><b>RESULTS</b>There were 130 STR alleles and 390 genotypes in the 15 STR of Maonan minority, with allele frequencies ranging from 0.0035 to 0.5385. The average heterozygosity was 0.7697, the discrimination power was higher than 0.8 except for that of TPOX, the accumulative discrimination power was more than 0.999999999, and the probability of paternity exclusion was more than 0.99999918.</p><p><b>CONCLUSION</b>The 15 STR loci of Maonan minority in Guangxi possesses the characteristics of high genetic diversity, except for the TPOX locus. They can be employed in minority genetics investigation, individual and paternity test in forensic medicine.</p>
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Polymorphism, Genetic
/
China
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Polymerase Chain Reaction
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Microsatellite Repeats
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Alleles
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Gene Frequency
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Genetics
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Genotype
Limits:
Adult
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Aged
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Aged, 80 and over
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Female
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Humans
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Male
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Chinese Journal of Medical Genetics
Year:
2007
Document type:
Article