The clinical efficacy of epristeride in the treatment of benign prostatic hyperplasia / 中华男科学杂志
National Journal of Andrology
; (12): 42-44, 2002.
Article
in Zh
| WPRIM
| ID: wpr-287208
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVES</b>To estimate the clinical safety, efficacy of Epristeride in the treatment of benign prostatic hyperplasia (BPH).</p><p><b>METHODS</b>One hundred and fourty-one BPH patients, aged from 50 to 83 years old [(66.18 +/- 6.41) yr], were given Epristeride tablets 5 mg p.o., twice daily for 120 days. To synthetically estimate the efficacy by the changing rate of international prostate symptom score (IPSS), maximum flow rate (Qmax), the volume of prostate (V) and the residual urine (Ru).</p><p><b>RESULTS</b>The total efficacy was 81.29%. The adverse reactions include 1 case (0.72%) of exanthem, 1 case (0.72%) of nausea and vomiting, 1 case (0.72%) of insomnia, 1 case (0.72%) of tinnitus and 3 cases (2.16%) of erectile dysfunction. Two patients discontinued the treatment due to the side effects (1.44%). There was no clinical significantly abnormal laboratory index during the treatment.</p><p><b>CONCLUSIONS</b>Epristeride tablets was safe and effective in the treatment of BPH.</p>
Full text:
1
Database:
WPRIM
Main subject:
Prostatic Hyperplasia
/
Treatment Outcome
/
Therapeutic Uses
/
Drug Therapy
/
Androstadienes
Limits:
Aged
/
Aged80
/
Humans
/
Male
Language:
Zh
Journal:
National Journal of Andrology
Year:
2002
Document type:
Article