Study on inhibitory effects of Taxus chinensis var. mairei aqueous extract on the proliferation of tumor cells / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
; (12): 805-809, 2013.
Article
in Zh
| WPRIM
| ID: wpr-287464
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the inhibitory effects of Taxus chinensis var. mairei Aqueous Extract (TAE) on SGC-7901 and MCF-7 cells, and to explore its mechanisms.</p><p><b>METHODS</b>The inhibitory effects of TAT and Paclitaxel on the proliferation of SGC-7901 and MCF-7 cells were tested by MTT method. Their effects on the morphology of SGC-7901 and MCF-7 cells were observed by microscope. Its effects on the cell apoptosis were detected by flow cytometry.</p><p><b>RESULTS</b>The TAE had inhibitory effects on the proliferation of tumor cells, and its mechanisms were correlated to inducing the apoptosis of tumor cells.</p><p><b>CONCLUSION</b>TAE had inhibitory effects on the proliferation of tumor cells.</p>
Full text:
1
Database:
WPRIM
Main subject:
Pharmacology
/
Plant Extracts
/
Chemistry
/
Apoptosis
/
Taxus
/
Cell Line, Tumor
/
Cell Proliferation
/
MCF-7 Cells
Limits:
Humans
Language:
Zh
Journal:
Chinese Journal of Integrated Traditional and Western Medicine
Year:
2013
Document type:
Article