Mortality Risk Factors for Patients with Septic Shock after Implementation of the Surviving Sepsis Campaign Bundles / 감염과화학요법
Infection and Chemotherapy
; : 199-208, 2016.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-28870
Responsible library:
WPRO
ABSTRACT
BACKGROUND:
Septic shock remains a leading cause of death, despite advances in critical care management. The Surviving Sepsis Campaign (SSC) has reduced morbidity and mortality. This study evaluated risk factors for mortality in patients with septic shock who received treatment following the SSC bundles. MATERIALS ANDMETHODS:
This retrospective cohort study included patients with septic shock who received treatments following SSC bundles in an urban emergency department between November 2007 and November 2011. Primary and secondary endpoints were all-cause 7- and 28-day mortality.RESULTS:
Among 436 patients, 7- and 28-day mortality rates were 7.11% (31/436) and 14% (61/436), respectively. In multivariate analysis, high lactate level (odds ratio [OR], 1.286; 95% confidence interval [CI], 1.016–1.627; P=0.036) and low estimated glomerular filtration rate (OR, 0.953; 95% CI, 0.913–0.996; P=0.032) were independent risk factors for 7-day mortality. Risk factors for 28-day mortality were high lactate level (OR, 1.346; 95% CI, 1.083–1.673; P=0.008) and high Acute Physiology and Chronic Health Evaluation II score (OR, 1.153; 95% CI, 1.029–1.293; P=0.014).CONCLUSION:
The risk of mortality of septic shock patients remains high in patients with high lactate levels and acute kidney injury.
Full text:
Available
Health context:
SDG3 - Target 3.3 End transmission of communicable diseases
Health problem:
Sepsis
Database:
WPRIM (Western Pacific)
Main subject:
Shock, Septic
/
Multivariate Analysis
/
Retrospective Studies
/
Risk Factors
/
Cohort Studies
/
Mortality
/
Cause of Death
/
Sepsis
/
APACHE
/
Lactic Acid
Type of study:
Etiology study
/
Incidence study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Humans
Language:
English
Journal:
Infection and Chemotherapy
Year:
2016
Document type:
Article