High bioactive material-bone graft in bone defect healing / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
; (6): 30-32, 2002.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-289329
Responsible library:
WPRO
ABSTRACT
OBJECTIVE:
To assese the value and clinical significance of bioactive material-hydroxyapatite (HA) combined with TGF-beta1 in bone defect healing.METHODS:
The applicability of bioactive material-HA granules combined with TGF-beta1 (group A) as a substitute for bone graft was observed in SD rat model. The results were compared with those of HA granules (Group B) and ungrafted bone defect (Group C).RESULTS:
Group A demonstrated the highest level of type I collagen mRNA during healing period.CONCLUSION:
The bioactive material-HA combined with TGF-beta1 can efficiently bond to ongrowing new bone comparing to HA granules.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Zhejiang University. Medical sciences
Year:
2002
Document type:
Article