Effects of etomidate infusion on serum cortisol in patients undergoing radical resection of lung cancer / 南方医科大学学报
Journal of Southern Medical University
; (12): 1047-1049, 2010.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-289996
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the effect of etodimate infusion on serum cortisol in patients undergoing radical resection of lung cancer operations during the perioperative period.</p><p><b>METHODS</b>Forty ASA I-II patients undergoing radical resection of lung cancer were randomly divided into etomidate group (Group E) and propofol group (Group P) (n=20). The serum cortisol was measured at 800 am (T(0)) before anesthesia, 400 pm (T(1)) on the day of operation and 24 h after the operation (T(2)) by radioimmunoassay.</p><p><b>RESULTS</b>Compared with that at T0, the serum level of cortisol significantly increased at 24 h after the operation in both groups (P<0.01); serum cortisol decreased lightly at T1, which was not statistically significant (P>0.05), and remained higher than the normal level. At each of the time points, serum cortisol levels were comparable between the two groups (P>0.05).</p><p><b>CONCLUSION</b>Etomidate infusion can not inhibit the synthesis of cortisol in patients undergoing radical resection of lung cancer.</p>
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Pneumonectomy
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Postoperative Period
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General Surgery
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Blood
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Hydrocortisone
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Etomidate
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Anesthesia, General
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Lung Neoplasms
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Methods
Limits:
Adult
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Female
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Humans
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Male
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2010
Document type:
Article