Effects on neuronal ultrastructure and nervous system of monkey after selective cerebral profound hypothermia and blood flow occlusion / 中华外科杂志
Chinese Journal of Surgery
; (12): 486-488, 2004.
Article
in Zh
| WPRIM
| ID: wpr-299940
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the effects of deep hypothermia on the neuronal ultrastructure and nervous system of monkey after selective cerebral profound hypothermia and blood flow occlusion.</p><p><b>METHODS</b>Brain-local extracorporeal circulation was established by right internal carotid artery deep hypothermic perfusion and homolateral external jugular vein backflow, brain blood flow was recovered from circulatory arrest 60 - 80 minutes late and monkey came back naturally.</p><p><b>RESULTS</b>In all 7 monkeys, 5 were succeeded in being build up the models except for 2 because of technic problems, and 4 of them lived up for ever. The function of nervous system grade, essential organ and neuronal ultrastructure were normal.</p><p><b>CONCLUSION</b>Selective cerebral profound hypothermia can increase the ability of brain to endure hypovolemia and hypoxidosis and prolong the time of blood flow occlusion.</p>
Full text:
1
Database:
WPRIM
Main subject:
Pathology
/
Time Factors
/
Brain Ischemia
/
Cerebrovascular Circulation
/
Haplorhini
/
Disease Models, Animal
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Extracorporeal Circulation
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Hypothermia, Induced
Type of study:
Prognostic_studies
Limits:
Animals
Language:
Zh
Journal:
Chinese Journal of Surgery
Year:
2004
Document type:
Article