Treatment of intractable epilepsy with hemispherectomy / 中华外科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To explore the clinical effectiveness of hemispherectomy for patients with intractable epilepsy.</p><p><b>METHODS</b>Thirty-six patients with intractable epilepsy were treated by modified hemispherectomy and their clinical results were followed up after operation.</p><p><b>RESULTS</b>The seizures of the 36 patients were effectively controlled and 34 (94.4%) were thoroughly controlled. Meanwhile, the dysfunction of the central nervous system in 30 patients (83.3%) was aggravated, and 5 patients (13.9%) showed better improvement than before. Neuropsychological assessment revealed much improvement in the patients.</p><p><b>CONCLUSIONS</b>Modified hemispherectomy is advisable for patients with wide-range lesion of the half-brain associated with intractable epilepsy.</p>