Epigenetics and neural stem cell commitment / 神经科学通报·英文版
Neuroscience Bulletin
; (6): 241-248, 2007.
Article
in En
| WPRIM
| ID: wpr-300957
Responsible library:
WPRO
ABSTRACT
Neural stem cell is presently the research hotspot in neuroscience. Recent progress indicates that epigenetic modulation is closely related to the self-renewal and differentiation of neural stem cell. Epigenetics refer to the study of mitotical/meiotical heritage changes in gene function that cannot be explained by changes in the DNA sequence. Major epigenetic mechanisms include DNA methylation, histone modification, chromatin remodeling, genomic imprinting, and non-coding RNA. In this review, we focus on the new insights into the epigenetic mechanism for neural stem cells fate.
Full text:
1
Database:
WPRIM
Main subject:
Physiology
/
Stem Cells
/
Cell Differentiation
/
Genomic Imprinting
/
DNA Methylation
/
Chromatin Assembly and Disassembly
/
Epigenesis, Genetic
/
Neurons
Limits:
Animals
/
Humans
Language:
En
Journal:
Neuroscience Bulletin
Year:
2007
Document type:
Article