Clinical study of percutaneous ultrasound-guided or freehand core needle biopsy of primary breast cancer / 中华外科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To evaluate ultrasound-guided or freehand percutaneous core needle biopsy in histopathological assessment of primary breast cancer lesions and its utility in primary breast cancer treatment.</p><p><b>METHODS</b>Retrospectively analysis of the clinical data of 697 primary breast cancer examined by mean of core needle biopsy.</p><p><b>RESULTS</b>The diagnostic accuracy, false negative rate and insufficiency rate was 90.5%, 8.9% and 0.6%, respectively. Diagnostic accuracy was significantly higher in ultrasound guiding comparing to palpable guiding (92.7% vs. 88.2%, P < 0.05). There was a nonsignificant trend toward increased false negative rate in palpable guiding (10.9% vs. 7.1%, P > 0.05).</p><p><b>CONCLUSION</b>Percutaneous core needle biopsy is reliable in histopathological assessment of primary breast cancer lesions. Ultrasound guiding was superior to palpable guiding in term of diagnostic accuracy in this study.</p>