Clinical study on integrative Chinese and Western medicine in treating allergic purpura and preventing renal impairment / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
; (12): 701-703, 2004.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-306807
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To observe the clinical effect in treatment of the recurrent allergic (Henoch-Schönlein) purpura and prevention of renal impairment by means of integrative Chinese and Western medicine (ICWM).</p><p><b>METHODS</b>One hundred and seventy-six children with allergic purpura were randomly divided into the treated group (Based on the Western routine therapy of the control group, Kangmin Xiaoban Yin, a kind of TCM decoction, was added for 7-10 days) and the control group. Levels of urinary beta2-microglobulin (beta2-MG) and serum IgA, IgE were measured before and after treatment. And clinical observation on the disappearance time (DT) of abdominal pain, arthralgia and purpura were implemented.</p><p><b>RESULTS</b>The DT of joint swelling, arthralgia, and purpura in the treated group was shorter than those in the control group, showing significant difference (P<0.01). Comparison between groups in urinary beta2-MG and serum IgA and IgE before treatment and 1 week after treatment were insignificantly different (P>0.05), but at 1 month and 6 months after treatment, the level of urinary beta2-MG in the treated group was lower than that in the control group, with significant difference (P<0.05), and levels of serum IgA and IgE at 1 month after treatment in the former were lower than those in the control group, also showing significant difference (P<0.05, P<0.01). Six-month recurreat rate in the treated group was 23.5%, while that in the control group. There was significant difference in comparison in 1/2-year recurrent rate (P<0.01).</p><p><b>CONCLUSION</b>ICWM in treating allergic purpura could reduce the repeated episodes and shorten the hospitalization time, and effectively prevent the renal impairment of the disease.</p>
Full text:
Available
Health context:
SDG3 - Health and Well-Being
Health problem:
Target 3.4: Reduce premature mortality due to noncommunicable diseases
Database:
WPRIM (Western Pacific)
Main subject:
IgA Vasculitis
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Urine
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Blood
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Immunoglobulin A
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Immunoglobulin E
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Prednisone
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Drugs, Chinese Herbal
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Beta 2-Microglobulin
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Therapeutic Uses
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Drug Therapy
Limits:
Adolescent
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Child
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Child, preschool
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Female
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Humans
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Male
Language:
Chinese
Journal:
Chinese Journal of Integrated Traditional and Western Medicine
Year:
2004
Document type:
Article