In vivo and in vitro studies on anode-oxidized titanium percutaneous implants / 生物医学工程学杂志
Journal of Biomedical Engineering
; (6): 93-96, 2006.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-309876
Responsible library:
WPRO
ABSTRACT
In order to solve the problesm in biological sealing of load-bearing percutaneous implants for a fairly long time, we investigated titanium with bioactivated anodic oxidized surface(group A) through the animal tests in vivo and the epithelium cell culture in vitro. Smooth Ti (group B) was used as control. The animal tests results showed that there was no evident difference in the inflammory reaction between the group A implant tissues and the group B implant/tissues. The bioactivated Ti surface could keep the implant not only bonding with the bone firmly but also adhering to the soft tissue closely, thus contributing to the formation of calcium phosphate layer and its micropores. The cell culture results also demonstrated that the microporous surface of group A could clasp and fix the skin. So, it can be concluded that the surface modified method of anode oxidization may be one of the most effective methods to resolve the problem of durable biological sealing.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Prostheses and Implants
/
General Surgery
/
Tibia
/
Titanium
/
Biocompatible Materials
/
Materials Testing
/
Cells, Cultured
/
Chemistry
/
Osseointegration
/
Coated Materials, Biocompatible
Limits:
Animals
Language:
Chinese
Journal:
Journal of Biomedical Engineering
Year:
2006
Document type:
Article