Manipulation of cofactor balance in microorganisms / 生物工程学报
Chinese Journal of Biotechnology
; (12): 16-26, 2017.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-310565
Responsible library:
WPRO
ABSTRACT
Cofactor balance plays an important role in producing enzymes, pharmaceuticals and chemicals. To meet the demand of industrial production, microbes should maintain a maximal carbon flux towards target metabolites without fluctuations in cofactor. We reviewed the physiological function of cofactor and discussed detailed strategies to manipulate cofactor balance through biochemical engineering and metabolic engineering. Furthermore, we indicated future research needs to further regulate cofactor balance.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Biotechnology
Year:
2017
Document type:
Article