Correlation between the refractory periods and threshold potentials and the spike programming in cortical neurons / 中国应用生理学杂志
Chinese Journal of Applied Physiology
; (6): 14-17, 2008.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-310817
Responsible library:
WPRO
ABSTRACT
<p><b>AIM</b>To investigate the intrinsic mechanisms underlying spike programming at pyramidal neurons and interneurons in layer II/III of sensorimotor cortex.</p><p><b>METHODS</b>Electrical signals at the cortical neurons were recorded in current clamp model with multi-clamp700B Amplifiers. Signals were inputted into pClamp and Origin for data acquisition and analyses.</p><p><b>RESULTS</b>Compared to pyramidal neurons, interneurons express the higher capacity of spikes and the more stability of spike programming, which are mechanistically caused by lower threshold potentials and shorter refractory periods.</p><p><b>CONCLUSION</b>The refractory periods and threshold potentials directly influence the programming of sequential spikes.</p>
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Physiology
/
Refractory Period, Electrophysiological
/
Action Potentials
/
Cerebral Cortex
/
Rats, Sprague-Dawley
/
Pyramidal Cells
/
Synaptic Transmission
/
Patch-Clamp Techniques
/
Cell Biology
/
Differential Threshold
Limits:
Animals
Language:
Chinese
Journal:
Chinese Journal of Applied Physiology
Year:
2008
Document type:
Article