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Clinical observation on focal vitiligo treated with heat-sensitive moxibustion in comparison with medication / 中国针灸
Article in Chinese | WPRIM (Western Pacific) | ID: wpr-314352
Responsible library: WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To observe the difference in clinical efficacy on focal vitiligo treated with heat-sensitive moxibustion in comparison with medication, and discuss its effect mechanism.</p><p><b>METHODS</b>Sixty-eight cases were randomized into a moxibustion group (38 cases) and a medication group (30 cases). Additionally, 20 healthy persons were selected randomly as a normal group. In the moxibustion group, the heat-sensitive moxibustion was applied to Hegu(LI 4), Quchi(LI 11), Yanglingquan(GB 34), Zusanli(ST 36), Xuehai(SP 10) and the others, once a day. In the medication group, triamcinolone acetonide cream was used externally and locally, twice a day. In the two groups, the treatment of 15 days made one session. The efficacy was observed after continuous treatment for 3 sessions. The hemorheology test was done in all of the subjects. The radioimmunoassay was adopted to determine the levels of Interleukin 2 (IL-2), Interleukin 6 (IL-6), Interleukin 10 (IL-10) and tumor necrosis factor (TNF-alpha) before and after treatment.</p><p><b>RESULTS</b>The levels of IL-6, IL-10 and TNF-alpha in vitiligo patients were higher significantly than those in the normal group (P<0. 01, P<0. 05), the level of IL-2 was lower significantly than that in the normal group (P<0. 01) before treatment. After 3 sessions treatment, IL-2 level was increased significantly in the moxibustion group and the levels of IL-6, IL-10 and TNF-alpha were reduced, without significant differences as compared with the normal group (all P>0. 05). But the differences were significant as compared with those in the medication group (all P<0. 05). The curative and remarkably effective rate was 76. 3% (29/38) after treatment in the moxibustion group, which was higher significantly than 13. 3% (4/30, P<0. 05) in the medication group.</p><p><b>CONCLUSION</b>Heat-sensitive moxibustion achieves very good clinical efficacy on focal vitiligo, which is probably via promoting blood circulation and regulating the levels of IL-6, IL-10 and TNF-alpha.</p>
Subject(s)
Full text: Available Database: WPRIM (Western Pacific) Main subject: Therapeutics / Vitiligo / Triamcinolone Acetonide / Tumor Necrosis Factor-alpha / Drug Therapy / Hot Temperature / Moxibustion Type of study: Controlled clinical trial / Diagnostic study Limits: Adolescent / Adult / Child / Female / Humans / Male Language: Chinese Journal: Chinese Acupuncture & Moxibustion Year: 2014 Document type: Article
Full text: Available Database: WPRIM (Western Pacific) Main subject: Therapeutics / Vitiligo / Triamcinolone Acetonide / Tumor Necrosis Factor-alpha / Drug Therapy / Hot Temperature / Moxibustion Type of study: Controlled clinical trial / Diagnostic study Limits: Adolescent / Adult / Child / Female / Humans / Male Language: Chinese Journal: Chinese Acupuncture & Moxibustion Year: 2014 Document type: Article
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