Desmoplastic small round cell tumor: report of 2 cases / 中华外科杂志
Chinese Journal of Surgery
; (12): 214-215, 2002.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-314895
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To recognize the characteristics of desmoplastic small round cell tumor (DSRCT) and improve the standard of diagnosis.</p><p><b>METHODS</b>We retrospectively reviewed the clinical data on the treatment of 2 patients with DSRCT in terms of their conditions, tissue sources, pathologic characteristics, immunohistochemical methods, clinical manifestation, diagnosis, treatment and prognosis.</p><p><b>RESULTS</b>Clinical manifestations were complicated. The 2 patients were mis diagnosed before operation. Their tumors consisted of irregular nests of small and round cells, with nuclear hyperchromatism and scant cytoplasm embedded in a plenty of fibrous connective tissues. The edge of the nest was clear, with different sizes and shapes. Immunohistochemically, the 2 patients were positive for CK or EMA, NSE, des and vim of the epithelium, nerve, muscle and interstitial. They died 9 months after operation.</p><p><b>CONCLUSIONS</b>The tumor may occur in the abdomen, pelvic cavity and other sites, with different clinical manifestations. Routine examination should be replaced by immunohistochemical test for correct diagnosis of the tumor. Prognosis of most patients is not good.</p>
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Immunohistochemistry
/
Retrospective Studies
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Carcinoma, Small Cell
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Diagnosis
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Neoplasms, Connective Tissue
Type of study:
Diagnostic study
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Observational study
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Prognostic study
Limits:
Adolescent
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Female
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Humans
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Male
Language:
Chinese
Journal:
Chinese Journal of Surgery
Year:
2002
Document type:
Article