Expression of matrixmetalloproteinase-8 on the bell-stage in human and rat tooth development / 华西口腔医学杂志
West China Journal of Stomatology
; (6): 26-28, 2004.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-319068
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the expression of MMP-8 in human and rat tooth development.</p><p><b>METHODS</b>Immunohistochemistry was used to detect the localization of MMP-8 protein while in situ hybridization was used to examine the expression of MMP-8 mRNA.</p><p><b>RESULTS</b>The expression of MMP-8 protein was localized in odontoblast and dentin matrix at the later bell stage in human tooth germ. The dentin was denser close to the pulp cavity. The expression of MMP-8 mRNA was found in very few polarized odontoblast at the early bell stage and all polarized odontoblast at the later bell stage in rat tooth germ.</p><p><b>CONCLUSION</b>The results suggested that MMP-8 involved in dentin matrix rebuilding in the process of dentin formation in human and rat dental development.</p>
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Tooth Germ
/
RNA, Messenger
/
Embryology
/
Rats, Sprague-Dawley
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In Situ Hybridization
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Matrix Metalloproteinase 8
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Dentin
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Embryo, Mammalian
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Genetics
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Animals, Newborn
Limits:
Animals
Language:
Chinese
Journal:
West China Journal of Stomatology
Year:
2004
Document type:
Article