Reasearch on mechanism of neurotrophins in discogenic low back pain / 中国骨伤
China Journal of Orthopaedics and Traumatology
; (12): 698-700, 2012.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-321878
Responsible library:
WPRO
ABSTRACT
Discogenic low back pain is the common type of chronic low back pain. However,its mechanism has not been completely clarified. Considerable evidence shows that neurotrophins play an important role in discogenic low back pain. The paper summarizes the mechanism of neurotrophins on discogenic low back pain according to the pain transfer pathway of neurotrophins in intervertebral disc, dorsal horn ganglia and spinal trigeminal nucleus. Changing the pain transmission by regulating neurotrophins and its receptor will provide a new way for the treatment of discogenic low back pain.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Trigeminal Nucleus, Spinal
/
Low Back Pain
/
Posterior Horn Cells
/
Intervertebral Disc
/
Metabolism
/
Nerve Growth Factors
Limits:
Humans
Language:
Chinese
Journal:
China Journal of Orthopaedics and Traumatology
Year:
2012
Document type:
Article