High intensity focused ultrasound combined with endocrine therapy in treating prostate cancer / 中华男科学杂志
National Journal of Andrology
; (12): 195-197, 2005.
Article
in Zh
| WPRIM
| ID: wpr-323398
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the clinical efficacy of high intensity focused ultrasound (HIFU) combined with endocrine therapy in the treatment of patients with prostate cancer.</p><p><b>METHODS</b>Twenty patients with prostate cancer were treated with extracorporeal HIFU device( model FEP-BY01 ) and androgen ablation, of whom 15 received orchiectomy and 5 LHRH-a. Fourteen patients of the total number were given flutamide in addition to castration.</p><p><b>RESULTS</b>The mean follow-up was 13.5 months (ranging 6 to approximately 30). Before and after the treatment, the prostate volume, prostate specific antigen (PSA), international prostate symptom score (IPSS) and maximal flow rate (Qmax) of the patients were (36.4 +/- 16.2) ml and (20.6 +/- 11.8) ml (P < 0.05), (32.2 +/- 10.4) ng/ml and (2.4 +/- 0.8) ng/ml (P < 0.01), 20. 5 +/- 6.5 and 13.6 +/- 7.5 (P < 0.05), (10.6 +/- 6.3) ml/s and (14.2 +/- 4.6) ml/s (P < 0.05), respectively. Mild hematuria and pain were noted in 5 and 8 patients respectively, and 1 patient underwent internal urethrotomy with a cold knife because of urethral stricture. er, with minimal complications.</p><p><b>CONCLUSION</b>HIFU combined with endocrine therapy is effective in the treatment of prostate canc-</p>
Full text:
1
Database:
WPRIM
Main subject:
Prostatic Neoplasms
/
Therapeutics
/
Orchiectomy
/
Follow-Up Studies
/
Gonadotropin-Releasing Hormone
/
Treatment Outcome
/
Combined Modality Therapy
/
Antineoplastic Agents, Hormonal
/
Ultrasound, High-Intensity Focused, Transrectal
/
Therapeutic Uses
Type of study:
Observational_studies
/
Prognostic_studies
Limits:
Aged
/
Aged80
/
Humans
/
Male
Language:
Zh
Journal:
National Journal of Andrology
Year:
2005
Document type:
Article