Progress of oligosaccharides biosynthesis in recombinant Escherichia coli / 生物工程学报
Chinese Journal of Biotechnology
; (12): 16-20, 2007.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-325425
Responsible library:
WPRO
ABSTRACT
As more bioactivities of oligosaccharides have been elucidated, researches on biosynthesis of oligosaccharides have drawn more concerns in Glycobiology. A lot of enzymatic methods for the synthesis of oligosacchrides have been developed employing recombinant E. coli expressed glycosyltranferase or synthase of nucleotide-sugar. This review focuses on the recent progress in the production of oligosaccharides using bacteria especially by genetically engineered bacteria. The key point concering the oligosaccharides biosynthesis in recombinant E. coli, such as enzyme expression, NDP-sugar provision and biosynthesis pathway, was discussed.
Full text:
Available
Health context:
Neglected Diseases
Health problem:
Neglected Diseases
/
Zoonoses
Database:
WPRIM (Western Pacific)
Main subject:
Oligosaccharides
/
Bacteria
/
Bacterial Proteins
/
Industrial Microbiology
/
Molecular Sequence Data
/
Genetic Engineering
/
Carbohydrate Sequence
/
Glycosyltransferases
/
Escherichia coli
/
Genetics
Language:
Chinese
Journal:
Chinese Journal of Biotechnology
Year:
2007
Document type:
Article