A novel orthopaedic biodegradable polymer and its biocompatibility

Jianguo LIU; Xin QI; Jikui GUAN; Xinxiang XU; Xuesi CHEN; Xiabin JING

A novel orthopaedic biodegradable polymer and its biocompatibility / 生物医学工程学杂志

Jianguo LIU; Xin QI; Jikui GUAN; Xinxiang XU; Xuesi CHEN; Xiabin JING.

Journal of Biomedical Engineering ; (6): 25-29, 2005.

Article in Chinese | WPRIM (Western Pacific) | ID: wpr-327142

Responsible library: WPRO

ABSTRACT

ABSTRACT

Copolymer of polycaprolactone (PCL) and polylactic acid (PLA) was synthesized and catalyzed using Y (CF3COO)3/AL (I-Bu)3. The biocompatibility was evaluated by means of biochemistry, immunocytochemistry, and by cytotoxity test. This novel orthopedic biodegradable polymer can serve as an ideal orthopedic biodegradable implants, and adjustment of molecular weight and ratio of polymers can control its degradation period.

Subject(s)

Animals; Female; Male; Rats; Absorbable Implants; Bone Substitutes; Catalysis; Lactic Acid; Chemistry; Materials Testing; Polyesters; Chemistry; Polymers; Chemistry; Rats, Wistar

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Full text: Available Database: WPRIM (Western Pacific) Main subject: Polyesters / Polymers / Materials Testing / Catalysis / Chemistry / Rats, Wistar / Bone Substitutes / Lactic Acid / Absorbable Implants Limits: Animals Language: Chinese Journal: Journal of Biomedical Engineering Year: 2005 Document type: Article

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