The research progress of one member of the EF-hand superfamily--troponin C / 生物工程学报
Chinese Journal of Biotechnology
; (12): 375-380, 2007.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-328020
Responsible library:
WPRO
ABSTRACT
The EF-hand superfamily is a large group of proteins which contain EF-hand motif formed by helix-loop-helix. These proteins always have the ability of binding metal ions or forming dimmers. Troponin C, known as having ability of binding Ca2+, is one member of the EF-hand superfamily. Troponin C interacts with troponin I and troponin T, forming a troponin complex which takes part in regulating muscle contraction. It is interesting that troponin C was also found in non-muscular tissue, and its function was proved to be different from that of troponin C found in muscular tissue. To date, a lot of researches about troponin C have been carried out widely. However, most of them focused on vertebrate, seldom were done on invertebrate. Our group carried out a research on troponin C from silkworm, a model organism of insects, aiming to clarify the structure and function of silkworm troponin C. Here, we mainly discuss the characters of the EF-hand superfamily and the classification, structure and function of troponin C . We also introduced our work about silkworm troponin C briefly, hoping of making a little contribution to the research of invertebrate troponin C.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Phylogeny
/
Protein Binding
/
Bombyx
/
Binding Sites
/
Molecular Sequence Data
/
Calcium
/
Amino Acid Sequence
/
Classification
/
Troponin C
/
EF Hand Motifs
Type of study:
Prognostic study
Limits:
Animals
Language:
Chinese
Journal:
Chinese Journal of Biotechnology
Year:
2007
Document type:
Article