Advanced achievements about neuroprotective mechanisms of paeoniflorin / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 1490-1493, 2010.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-328091
Responsible library:
WPRO
ABSTRACT
Paeoniflorin is one of the bioactive components of Paeonia lactiflora, a traditional Chinese herbal medicine. Some recent studies prove its distinguished neuroprotective effect. These neuroprotective mechanisms have become hot points and show closely correlated to activating adenosine A1 receptor, ameliorating the function of cholinergic nerve, regulating ion channel homeostasis, retarding oxidative stress and apoptosis of the neurocytes, promoting nerve growth, having an influence on astrocytes and being ableto penetrate though blood brain barrier. In this review, we present the neuroprotective mechanisms of paeoniflorin in the following eight aspects.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Benzoates
/
Bridged-Ring Compounds
/
Drugs, Chinese Herbal
/
Chemistry
/
Apoptosis
/
Oxidative Stress
/
Neuroprotective Agents
/
Paeonia
/
Cell Biology
Limits:
Animals
/
Humans
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2010
Document type:
Article