Heat injury induced apoptosis in rat striatum neurons / 中国应用生理学杂志
Chinese Journal of Applied Physiology
; (6): 342-344, 2004.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-330101
Responsible library:
WPRO
ABSTRACT
<p><b>AIM</b>To investigate the effect of hyperthermia on apoptosis of cultivated striatum neurons in the rat.</p><p><b>METHODS</b>After 30 min hyperthermia in 43 degrees, the Ca2+ concentration, the mitochondria membrane potential of the neuron were detected by Laser Scanning Confocal Microscopy (LSCM). The apoptosis of striatum neurons was detected by TUNEL staining.</p><p><b>RESULTS</b>Heat stress at 43 degrees C for 40 min caused an increase in the Ca2+ concentration of striatum neurons and a decrease in the mitochondria membrane potential of the striatum neurons.</p><p><b>CONCLUSION</b>The striatum shows more apoptosis neurons after heat stress.</p>
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Cells, Cultured
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Rats, Wistar
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Apoptosis
/
Heat-Shock Response
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Corpus Striatum
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Cell Biology
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Membrane Potential, Mitochondrial
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Hot Temperature
/
Animals, Newborn
Limits:
Animals
Language:
Chinese
Journal:
Chinese Journal of Applied Physiology
Year:
2004
Document type:
Article