Splenic lymphangioma: clinicopathologic and immunohistochemical study of 18 cases and review of literature / 中华病理学杂志
Chinese Journal of Pathology
; (12): 98-101, 2007.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-333960
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the clinicopathologic features and differential diagnosis of splenic lymphangioma.</p><p><b>METHODS</b>Eighteen cases of splenic lymphangioma were retrieved from the pathology archives during the period between January 1990 to December 2005. The clinicopathologic features were analyzed. Immunohistochemical study was performed on the paraffin sections of 16 cases.</p><p><b>RESULTS</b>The age of the patients ranged from 9 to 72 years (median = 40 years). Thirteen patients were males and 5 were females. Clinically, the tumor could be asymptomatic or present with abdominal symptoms and hypersplenism. Follow-up information was available in 13 patients (72.2%) and the duration varied from 5 months to 15 years. All 13 patients had an uneventful clinical course, with no evidence of residual disease, local recurrence or metastasis. Gross examination showed splenic enlargement. The tumor appeared as cystic (8/18), solid (5/18) or honeycomb mass (5/18), either solitary (5/18) or multifocal (13/18). Histologically, splenic lymphangioma could be subclassified as cavernous (9/18), cystic (5/18) or mixed (4/18). Immunohistochemical study showed that the positivity rates for CD9 and D2-40 were 100% and 43.8% respectively.</p><p><b>CONCLUSIONS</b>Splenic lymphangioma is a rarely encountered entity that can be misdiagnosed as a splenic hemangioma. A definite diagnosis depends on pathologic examination.</p>
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Splenectomy
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Splenic Neoplasms
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General Surgery
/
Immunohistochemistry
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Membrane Glycoproteins
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Biomarkers, Tumor
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Antigens, CD
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Follow-Up Studies
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Lymphangioma, Cystic
Type of study:
Diagnostic study
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Observational study
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Prognostic study
Limits:
Adult
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Aged
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Child
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Female
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Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Pathology
Year:
2007
Document type:
Article