Effect of Helicobacter pylori eradication on childhood acute idiopathic thrombocytopenic purpura / 南方医科大学学报
Journal of Southern Medical University
; (12): 1243-1244, 2009.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-336100
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the effect of Helicobacter pylor (Hp) eradication in children with acute idiopathic thrombocytopenic purpura (ITP).</p><p><b>METHODS</b>Ninety-three children with acute ITP and Hp infection were divided into two groups and treated with prednisone and Hp eradication (group A, 51 cases) or with prednisone without Hp eradication (group B, 42 cases).</p><p><b>RESULTS</b>The Hp eradication rate was 94.1% in group A. No difference was found in the therapeutic effects on IPT between the two groups, but the recurrence rate in one year in group A was significantly lower than that in group B.</p><p><b>CONCLUSION</b>NHp eradication does not obviously enhance the therapeutic effect on childhood acute ITP, but can decrease the relapse rate in one year. HP eradication therapy is recommended in children with acute ITP and Hp infection.</p>
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Prednisone
/
Helicobacter pylori
/
Helicobacter Infections
/
Purpura, Thrombocytopenic, Idiopathic
/
Therapeutic Uses
/
Drug Therapy
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Drug Therapy, Combination
/
Allergy and Immunology
/
Microbiology
/
Anti-Bacterial Agents
Limits:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2009
Document type:
Article