Yin-yang relationship between oncogene and antioncogene / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
; (12): 72-75, 2009.
Article
in Zh
| WPRIM
| ID: wpr-337546
Responsible library:
WPRO
ABSTRACT
Oncogene and antioncogene play contrary effects on the cell growth and proliferation controlling process, and cancer occurs when the presence of imbalance expression between them. That means there is yin-yang relationship between oncogene (yang) and antioncogene (yin), and also inside both of them. Taking the oncogene myc and antioncogene p53 for example, the yin gene p53 acts, in the yin side, to promote cell apoptosis and inhibit cell growth, while in the yang side, it facilitates for repairing the injured DNA to keep cell survival; the yang gene myc, promoting cell growth and proliferation in the yang side and inducing cell apoptosis in the yin side. To elucidate the yin-yang reactions between oncogene and antioncogene would be of important significance in the all-round and profound research of cancer.
Full text:
1
Database:
WPRIM
Main subject:
Oncogenes
/
Genes, Tumor Suppressor
/
Tumor Suppressor Protein p53
/
Proto-Oncogene Proteins c-myc
/
Yin-Yang
/
Genetics
/
Medicine, Chinese Traditional
/
Metabolism
/
Neoplasms
Type of study:
Diagnostic_studies
Limits:
Humans
Language:
Zh
Journal:
Chinese Journal of Integrated Traditional and Western Medicine
Year:
2009
Document type:
Article