MLST typing of Streptococcus suis isolated from clinical patients in Guangdong Province in 2005 / 南方医科大学学报
Journal of Southern Medical University
; (12): 1438-1441, 2008.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-340800
Responsible library:
WPRO
ABSTRACT
Intensive surveillance of human S.suis infection was carried out in July and August of 2005 in Guangdong Province, which coincided with the Sichuan outbreak. Five isolated cases of human infections were identified during this period, from which 5 S. suis serotype 2 isolates were recovered. MLST analysis showed that these 5 isolates shared identical sequences of 6 MLST housekeeping genes except for one point mutation found within the thrA gene fragment, a neutral mutation (TTA to TTG) in the third nucleotide (360 nt) of the codon for leucine. MLST analysis identified 2 sequence types in the Guangdong sporadic infection. Three Guangdong isolates L-SS002, L-SS003 and L-SS005 belonged to ST7, while the other two isolates L-SS004 and L-SS006 belonged to ST1, but they all belonged to ST1 clonal complex. This finding represents a striking feature that differs from the Sichuan outbreak caused by a single ST7 SS2 clone. The 3 isolates of ST7 were probably imported from Sichuan Province, while the origin of the other 2 isolates of ST1 still remain to be clarified.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Streptococcal Infections
/
Swine
/
Swine Diseases
/
Virulence
/
DNA, Bacterial
/
Zoonoses
/
China
/
Bacterial Typing Techniques
/
Streptococcus suis
/
Classification
Type of study:
Prognostic study
Limits:
Animals
/
Humans
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2008
Document type:
Article