Advances in the study of steroidogenic acute regulatory protein / 中华男科学杂志
National Journal of Andrology
; (12): 733-736, 2006.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-343531
Responsible library:
WPRO
ABSTRACT
The steroidogenic acute regulatory (StAR) protein is an essential component in the regulation of steroid biosynthesis in adrenal and gonadal cells. The StAR protein has a high tissue specificity, located on the mitochondrial membranes of some relative cells. It regulates the transfer of cholesterin from extracellular into intracellular and plays a dominant role in steroidogenic synthesis. Recent studies have also shown that the transcription and expression of StAR are modulated not only through the cAMP-PKA dependent pathway, but also by multiple hormones and cytokines, which contributes to the regulation of cholesterin synthesis.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Phosphoproteins
/
Physiology
/
Cholesterol Side-Chain Cleavage Enzyme
/
Gene Expression Regulation
/
Cholesterol
/
Ethisterone
/
Genetics
/
Metabolism
/
Mitochondria
Limits:
Animals
/
Humans
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2006
Document type:
Article