A new trincallane derivative from Salacia hainanensis Chun et How / 药学学报
Acta Pharmaceutica Sinica
; (12): 1123-1126, 2009.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-344046
Responsible library:
WPRO
ABSTRACT
Chemical constituents of the roots and stem of Salacia hainanensis Chun et How were isolated and purified with column chromatography on silica gel, Sephadex LH-20 and preparative HPLC. Their structures were elucidated based on physicochemical and spectral spectroscopic analysis. Depending on the activities of anti-alpha-glucosidase and inhibiting AGEs (advanced glycation end products, AGEs) formation in vitro, nine compounds were identified as 26, 27-dihydroxy-7, 24-tirucalladien-3-one (1), abruslactone A (2), lupeol (3), 21alpha, 30-dihydroxy-D A-friedooleanan-3-one (4), 15alpha-hydroxyfriedelan-3-one (5), friedelin (6), mangiferin (7), epicatechin (8) and beta-sitosterol (9), separately. Among them, compound 1 is a new compound, and compound 2 was isolated from the Salacia genus for the first time, while, compounds 3, 4, 5, 8 were obtained from this plant for the first time.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Plants, Medicinal
/
Steroids
/
Triterpenes
/
Molecular Structure
/
Catechin
/
Chemistry
/
Plant Stems
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Plant Roots
/
Xanthones
/
Salacia
Language:
Chinese
Journal:
Acta Pharmaceutica Sinica
Year:
2009
Document type:
Article