Distribution and antibiotic resistance of pathogens isolated from children with infectious diarrhea in Guangzhou / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
; (12): 107-109, 2009.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-347990
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the distribution and antibiotic resistance of the isolated pathogens from children with infectious diarrhea in Guangzhou.</p><p><b>METHODS</b>The fecal samples of 2 409 children with infectious diarrhea between January 2006 and December 2007 were collected and cultured. Pathogenic bacterium were isolated and identified by biochemical and serological methods. The antibiotic susceptibilities were tested by the Kirby-Bauer method.</p><p><b>RESULTS</b>A total of 448 isolates of pathogenic bacterium (18.6%) were obtained, including Shigella (n=159), enteropathogenic Escherichia coli (n=141), Salmonella (n=76), Vibrion (n=11), fungus (n=41), and C jejuni (n=20). All of isolates of the three major pathogenic bacterium, Shigella, enteropathogenic Escherichia coli and Salmonella, were susceptible to imipenem and less than 10% of the isolates were resistant to the third generation cephalosporins and beta-lactamase inhibitors. However, the isolates showed a high resistance to ampicillin and sulfamethoxazole/trimethoprim (>75%).</p><p><b>CONCLUSIONS</b>Shigella, enteropathogenic Escherichia coli and Salmonella were major pathogenic bacterium of diarrhea in children from Guangzhou. The major isolates were susceptible to imipenem, the third generation cephalosporins and beta -lactamase inhibitors, but were resistant to ampicillin and sulfamethoxazole/trimethoprim.</p>
Full text:
Available
Health context:
Neglected Diseases
Health problem:
Diarrhea
/
Neglected Diseases
Database:
WPRIM (Western Pacific)
Main subject:
Bacteria
/
Drug Resistance, Microbial
/
Diarrhea
/
Drug Therapy
/
Fungi
/
Microbiology
Limits:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Language:
Chinese
Journal:
Chinese Journal of Contemporary Pediatrics
Year:
2009
Document type:
Article