Glutathione S-transferase polymorphisms and male infertility / 中华男科学杂志
National Journal of Andrology
; (12): 266-269, 2013.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-350897
Responsible library:
WPRO
ABSTRACT
The pathogenesis of male infertility involves the interactions between environmental and genetic factors. An individual's susceptibility to male infertility is influenced by his internal abilities of metabolizing and detoxicating endogenous and exogenous chemicals. Glutathione-S-transferases (GSTs), such as enzymes, are involved in the cellular detoxication of various physiological and xenobiotic substances. Studies show that the polymorphism of the GSTs gene is correlated with male infertility. GSTs polymorphism-related susceptibilities to male infertility were found similar but with some inconsistencies within the same community, and inconsistent with some similarities among different communities. Therefore, further studies are to be done on the differences in GSTs polymorphism-related susceptibility to male infertility in different communities.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Polymorphism, Genetic
/
Genetic Predisposition to Disease
/
Genetics
/
Genotype
/
Glutathione Transferase
/
Infertility, Male
Limits:
Humans
/
Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2013
Document type:
Article