Quantitative and qualitative evaluation on tablets of Ginkgo biloba leaves using fingerprint and LC-MS analysis / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 1738-1743, 2015.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-351274
Responsible library:
WPRO
ABSTRACT
A reasonable method for the quality control of tablets of Ginkgo biloba leaves was established in this paper. The total flavonol glycosides and terpene lactones of G. biloba tablets were quantified by HPLC. Totally, 16 batches of the commercially available tablets of G. biloba leaves were determined. Among of them, 2 batches were unqualified in the content of total flavonol glycosides, and 3 batches were unqualified in the content of terpene lactones. A validated HPLC fingerprint method was established to evaluate the commercially available tablets of G. biloba leaves with the assistance of LC-MS. Sixteen batches showed the similarity of 0.763-0.989. There were 31 fingerprint chromatogram peaks were identified as flavonoids compositions by LC-MS. This provides a research idea for the quality control of tablets of G. biloba leaves.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Quality Control
/
Mass Spectrometry
/
Tablets
/
Drugs, Chinese Herbal
/
Chemistry
/
Chromatography, High Pressure Liquid
/
Plant Leaves
/
Ginkgo biloba
/
Methods
Type of study:
Qualitative research
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2015
Document type:
Article
