Clinical Applications of Multifocal Electroretinography (mfERG)

ABSTRACT

PURPOSE: To compare the multifocal electroretinography (mfERG) system to full-field ERGs obtained from patients with known retinal diseases in order to assess its clinical applicability. METHODS: Full-field ERGs, mfERG, fluorescein angiography, visual field examination were performed in normal person and in patients with retinitis pigmentosa, nonischemic central retinal vein occlusion, branch retinal vein occlusion, Vogot-Koyanagi-Harada syndrome, central serous chorioretinopathy, macular degeneration or retinal detachment. RESULTS: The dysfunctional areas measured by mfERG were well compatible to those assumed by findings of full-field ERGs. However, the results of mfERG in the retina with central serous chorioretinopathy were shown abnormal response despite of normal response of full-field ERGs. The results of mfERG in the retina with macular degeneration showed abnormal response although other findings (e.g. Full-filed ERGs, FAG, Fundus ) were normal. CONCLUSIONS: The mfERG system is useful for electroretinographic field mapping and evaluating retinal function clinically.