Study on chronical hepatitis B with treatment of integrative traditional Chinese and Western medicine / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 1277-1280, 2006.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-356725
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study curative effect of chronical hepatitis B with treatment of integrative traditional Chinese and western medicine.</p><p><b>METHOD</b>115 cases of HBeAg and/or HBVDNA positive chronical hepatitis B were randomly divided into two groups in control. The first group treated by traditional Chinese medicine (TCM)-Fufang Huangqi granule and the second treated by intergrative traditional Chinese and western medicine (ICWM)-Fufang Huangqi granule and lamivudine for at least 24 weeks.</p><p><b>RESULT</b>The positive rate of HBVDNA at 12, 24 weeks, and the positive rate of HBeAg at 24 weeks in TCM are markedly lower than those of before treatment (P < 0.01). The positive rate of HBeAg and the positive rate of HBVDNA in ICWM are markedly lower than those of before treatment both at 12, 24 weeks (P < 0.01). The average values of HBVDNA are markly lower than before treatment in two groups at both 12,24 weeks (P < 0.01). At 12 weeks, the negative-turning rate of HBVDNA in the ICWM group is 79.17%, which shows significant difference in comparision with 40.00% in the TCM group (P < 0.01). The negative-turning rate of HBeAg in the ICWM group is 26.92%, which shows no significant difference in comparision with 32. 08% in the TCM group. At 24 weeks, the negative-turning rate of HBVDNA in the ICWM group is 85.71%, which shows significant difference in comparision with 50.00% in the TCM group (P < 0.01). The negative-turning rate of HBeAg in the ICWM group is 36.36%, which shows no significant difference in comparision with 28.57% in the TCM group. At 12 weeks,the total effective rate of the ICWM group is 96. 43%, which shows significant difference in comparision with 71.26% in the TCM group (P<0.01). At 24 weeks, the total effective rate of the ICWM group is 88. 00%, which shows significant difference in comparision with 67.61 % in the TCM group (P < 0.01). The average values of ALT and AST are markly improved than those of before treatment in two groups (P < 0.01). The average values of ALB is markly higher than before in TCM groups after 24 weeks treatment (P < 0.01).</p><p><b>CONCLUSION</b>Fufang Huangqi granule integrated with lamivudine possesses a better effect for counteracting the hepatitis B virus and improving the liver functioin than only itself.</p>
Full text:
Available
Health context:
SDG3 - Health and Well-Being
Health problem:
Target 3.3: End transmission of communicable diseases
Database:
WPRIM (Western Pacific)
Main subject:
Plants, Medicinal
/
Blood
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DNA, Viral
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Drugs, Chinese Herbal
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Chemistry
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Hepatitis B virus
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Lamivudine
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Anti-HIV Agents
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Hepatitis B, Chronic
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Astragalus propinquus
Limits:
Adolescent
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Adult
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Aged
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Female
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Humans
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Male
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2006
Document type:
Article