Quality standard for Xindi soft capsule / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 552-597, 2006.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-356772
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To establish the quality control standard of Xindi soft capsule.</p><p><b>METHOD</b>Quercetin, kaempferol and isorhamnetin were isolated by TLC with chloroform-ethyl formate-formic acid (541). The chromatographic separation was performed on a Diamonsil C18 column (4.6 mm x 250 mm, 5 microm). Acetonitrile-water-phosphoric (30700.1) as mobile phase. The flow rate was 1 mL x min(-1) and column temperature was set at 40 degrees C. The UV detection wavelength was set at 254 nm.</p><p><b>RESULT</b>Quercetin, Kaempferol and Isorhamnetin could be identified by TLC. Quercetin showed a good linear relationship at a range of 0.412-1.648 microg, r = 0.999 9, the average recovery was 96.8%, and RSD was 0.9% (n = 6). Kaempferol showed a good linear relationship at a range of 0.021-0.083 microg, r = 0.999 8, the average recovery was 96.9%, and RSD was 2.0% (n = 6). Isorhamnetin showed a good linear relationship at a range of 0.183-0.732 microg, r = 0.999 9, the average recovery was 97.1%, and RSD was 1.6% (n = 6).</p><p><b>CONCLUSION</b>The method is accurate with the good reproducibility and can be used for the quality control of Xindi soft capsule.</p>
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Plants, Medicinal
/
Quality Control
/
Quercetin
/
Reference Standards
/
Capsules
/
Drugs, Chinese Herbal
/
Chemistry
/
Reproducibility of Results
/
Chromatography, Thin Layer
/
Hippophae
Type of study:
Prognostic study
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2006
Document type:
Article