Treatment for Malignant Exophthalmos with or without Thyroid Abnormality by Kampo, Japanese Traditional Medicine / 日本東洋医学雑誌

ABSTRACT

Two cases of malignant exophthalmos, one with and the other without thyroid abnormality, were treated with Kampo, Japanese traditional medicine. Case 1-62 years old female complained of exophthalmos (r 23mm, l 22mm), visual disturbance (visual acuity r 0.1, l 0.5), total ophthalmoplegia, hyperemia and edema of the eye lids and conjunctiva without thyroid function abnormality, was treated by the administration of <I>Ryokeijutsukanto</I> and <I>Tokishakuyakusan</I> without any other medications. Seven days after the administration, the exophthalmos was reduced (r 21mm, l 20mm), the visual acuity improved (r 0.6, l 0.7), the hyperemia and edema of the eye lids and conjunctiva almost disappeared and the eye movement improved toward normal. Case 2-66 years old male complained of exopthalmos, ophthalmoplegia, hyperemia and edema of the eye lids and conjunctiva with euthyroid Graves' disease was treated by the administration of <I>Ryokeijutsukanto</I> and <I>Tokishakuyakusan</I> followed by improvement of the visual acuity and the eye movement, and reduction of the hyperemia and edema of the eye lids and conjunctiva.<BR>These observations suggest that treatment with Kampo can be effective in malignant exophthalmos with or without thyroid abnormality.