MicroRNA and cancer / 国际肿瘤学杂志
Journal of International Oncology
; (12): 883-885, 2010.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-385657
Responsible library:
WPRO
ABSTRACT
MicroRNAs (MiRNAs) are a contemporary class of short non-coding RNAs,which play a critical role in diverse biological processes, including development, cell proliferation, differentiation, and apoptosis,by suppressing translation of protein coding genes, or cleaving target mRNAs of protein coding genes to induce their degradation. Accordingly, altered miRNA expression is likely to contribute to human disease, including cancer. This review will summarize the emerging knowledge of the association between human miRNA biology and different aspects of carcinogenesis, such as the development, metastesis and therapy strategies.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of International Oncology
Year:
2010
Document type:
Article