The application of glucose damp technique on the children endocrine field / 国际儿科学杂志

ABSTRACT

Insulin sensitivity and insulin secretion function are the hot spots for studying the sugar and lipid metabolism. Hyperinsulinemic euglycemic clamp and hyperglycemic clamp are the gold standard for insulin sensitivity test and insulin secretion function test. Lack of insulin secretion and insulin resistance are the two main pathogenesis of diabetes. Adopting glucose clamp technology to explore diabetes and diabetic complications, and other endocrine diseases has bocome the main method. Recently,this technology has been initially used in childhood diabetes,obesity, short stature syndrome, metabolic syndrome, et al. Hie technology becomes common in children with endocrine diseases.