Experimental Study on the Anti-contact Dermatitis Efficacy and Antiviral Effect of JingFuYe / 国际中医中药杂志

ABSTRACT

Objective To discuss the antiviral effect and anti-contact dermatitis efficacy of JingFuYe. Methods Made contact dermatitis mice model by DNFB, measured the central thickness of mice left ear in each medication group and adopted the ABC immunohistochernical method to detect the number of Langerhan spcell(LCs). Infect guinea pig vaginal by HSV-2. Changes of symptoms were evaluated by Symptom score method. Detect the number of HSV-IgG and IgM in guinea pig serum. Results Compared with the control group, the ear thickness difference and the number of LCs in the experimental group were significantly reduced. JingFuYe have inhibitive effect to the Lesions caused by HSV-2 vaginal infection in guinea pig On different extents. Conclusion JingFuYe has inhibitive function to the murine experimental contact dermatitis and anti-virus effects.