The effects of levocitirize dihydrochloride on serum IL-13 and IL-18 in patients with cough variant asthma / 中国基层医药
Chinese Journal of Primary Medicine and Pharmacy
; (12): 445-446, 2009.
Article
in Zh
| WPRIM
| ID: wpr-395646
Responsible library:
WPRO
ABSTRACT
Objective To explore the effects of Levoeitirize dihydrochloride on interleukin-13(IL-13)and interleukin-18(IL-18)in the serum of the patients with cough variant asthma(CVA).Methods 70 cases with CVA were randomly devided into control group of 35 cases and treatment group of 35 cases.Control group was given Chlort rimeton and the treatment group was given Levocitirize dihydroehloride.The levels of IL-13 and IL-18 in the serum were measured before and after treatment.Results After treatment,the concentrations of IL-13 and IL-18 in patients in the treatment group were(46.7±17.3)ng/L and(145.2±27.1)ng/L,and those in the control group were(98.5±30.7)ng/L and(179.6±30.5)ne/L,which were significantly improved.Conclusion The treatmem of Levoeitirize dihydrochloride could improve the CVA through improving the production of IL-13 and IL-18.
Full text:
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Database:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Primary Medicine and Pharmacy
Year:
2009
Document type:
Article