Effect of Panax notoginseng saponins on anti-platelet aggregation / 国际外科学杂志
International Journal of Surgery
; (12): 38-40, 2009.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-396900
Responsible library:
WPRO
ABSTRACT
Objective To observe the effects of Panax notoginseng saponins and aspirin on platelet aggregation and analyzed resistance probability.Methods One hundred and twenty patients with cerebral infarction were di-vided randomly into Panax notoginseng saponins group and the aspirin group (each group 30 cases),respectively treated with adenosine diphosphatc (ADP),arachidonic acid (AA) to induced and detect the largest platelet aggre-gation (MAR).All patients received platelet aggregation test in hospital on the first and 14th day.Results In Pa-nax notoginseng saponins group and the aspirin group platelet aggregation induced by gents in the same role did not show statistical significance.There were resistances,semi-resistance phenomenon.Conclusions Panax notogin-seng saponins on platelet aggregation and the impact of aspirin was not significant; it may be used as anti-platelet aggregation drug,but there is also the resistance phenomenon.By combining Panax notoginseng saponins other an-ti-platelet drug anti-platelet aggregation of the long-term clinical.It might solve the resistance problem through large-scale clinical trials.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Surgery
Year:
2009
Document type:
Article